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Rapid expansion of respiration therapy

Low-cost pressurized helmets for non-invasive CPAP ventilation of COVID-19 patients

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The Oregon State University Fast Response Respiration (OFRR) initiative is addressing an acute global shortage of ventilators by providing affordable and scalable options for treating COVID-19 patients.

The OFRR team has identified a pathway to produce more than 100,000 ventilation systems per month—equal to the total current U.S. supply of ventilator machines. Proven effective in treating mild-to-moderate Acute Respiratory Distress Syndrome (ARDS), these non-invasive ventilation (NIV) systems can be used directly with hospital oxygen with no additional equipment needed.

    Helmet noninvasive ventilation using wall gases

    The pressurized helmet solution uses a pressurized medical helmet that is already an FDA-registered and listed device used in hospitals for more than a decade.

    Information for clinical practitioners

    White paper

    "Helmet Noninvasive Ventilation using Wall Gases: Sparing Ventilators during the 2020 Coronavirus Pandemic" by John Gotchall, MD. Designed to assist in-servicing helmet NIV using wall gases.

    University of Chicago resources

    Access to various articles and videos from this global-leading research effort on the use of helmets for respiratory application of helmet.

    Helmet Ventilation
    A detailed video curating the best practices for the management of helmet ventilation prepared by Bhakti Patel, MD, University of Chicago. April 2020. (25 min)

    Helmet Ventilation Reduces the Need for Endotracheal Ventilation in ARDS
    This 2017 Clinical Research Forum Distinguished Clinical Research Achievement Awards-winning study, led by Dr. Bhakti Patel from the University of Chicago, found that the use of a helmet for treatment of patients with ARDS reduced the need for ventilator use compared to the use of the standard face mask, and also prevented one death out of every five patients. (1.5 min)

    Relevant literature

    Zotero listing of relevant literature
    (Please send OFRR additional citations to add)

    Bill of materials

    Download the bill of materials

    Information for manufacturers and equipment developers

    Relevant patents

    Zotero listing of relevant patents

    FDA requirements and process

    Additional web resources